Study: CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes

Immunoglobulin G (IgG) antibody subclasses play major roles in the control of bacterial and viral infections, the killing of tumour cells during antibody therapy and the pathological destruction of healthy tissues in autoimmune diseases. As a result of their potency and range of actions, antibodies have become one of the most rapidly growing classes of human therapeutics in recent years, particularly in cancer treatments.